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Search Results for " RNA helicase "

ターゲット

9

阻害剤

20

リコンビナントタンパク質

1

ライブラリー

カタログ番号 製品名 別名 ターゲット
T16961 Supinoxin RX-5902 Apoptosis , DNA/RNA Synthesis
Supinoxin (RX-5902) is an orally active inhibitor of phosphorylated-p68 RNA helicase and a potent first-in-class anti-cancer agent. Supinoxin induces cell apoptosis and inhibits the growth of TNBC cancer cell lines (IC50...
T9168 NSC 617145 NSC617145,NSC-617145 DNA/RNA Synthesis
NSC 617145 (NSC617145) is an inhibitor of WRN helicase that inhibits the ATPase, but not exonuclease, activity of WRN helicase in a concentration-dependent manner.
T5413 ML216 CID-49852229 DNA/RNA Synthesis
ML216 (CID-49852229) is a small molecule inhibitor of BLM helicase (IC50: 1.8 μM). It showed 28-fold selective against the related helicases RECQ1, RECQ5, and E. coli UvrD (IC50s > 50 μM).
T2275 YK-4-279 Apoptosis , DNA/RNA Synthesis
YK 4-279, an inhibitor of RNA Helicase A (RHA), binds to the oncogenic transciption factor EWS-FLI1.
T82568 DHX9-IN-2 DNA/RNA Synthesis
DHX9-IN-2 is an inhibitor targeting ATP-dependent RNA de-helicase A (DHX9) with anticancer and antitumor activity for cancer research.
T6970 RK33 RK-33,RK 33 COX
RK33 (RK 33) is a first-in-class small molecule inhibitor of DDX3 (a RNA helicase) and causes G1 cell cycle arrest, induces apoptosis, and promotes radiation sensitization in DDX3-overexpressing cells.
T22282 Brr2-IN-3 Brr2 Inhibitor 9,Brr2 Inhibitor C9 Others
Brr2-IN-3 (Brr2 Inhibitor C9) is an allosteric inhibitor of the spliceosomal RNA helicase Brr2. Brr2 is implicated in autosomal-dominant retinitis pigmentosa (a group of progressive retinal degenerative disorders).
T10848 CMLD012073 Others
T82569 DHX9-IN-1
DHX9-IN-1 is a potent ATP-dependent RNA helicase A (DHX9) inhibitor, exhibiting an IC50 of 9.45 nM and demonstrating antitumor activity [1].

Recombinant Proteins

カタログ番号 製品名 Species Expression System
TMPH-00974 DHX9 Protein, Human, Recombinant (His & SUMO) Human E. coli
DHX9 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli.
TMPH-01900 DDX5 Protein, Human, Recombinant (His & Myc) Human E. coli
DDX5 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 74.1 kDa and the accession number is P17844.
TMPH-00980 DHX33 Protein, Human, Recombinant (His) Human E. coli
DHX33 Protein, Human, Recombinant (His) is expressed in E. coli.
TMPH-02133 DDX39B Protein, Human, Recombinant (GST) Human E. coli
Involved in nuclear export of spliced and unspliced mRNA. Assembling component of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and specifically associates with spliced mR...
TMPH-01902 DDX60 Protein, Human, Recombinant (His) Human E. coli
Positively regulates DDX58/RIG-I- and IFIH1/MDA5-dependent type I interferon and interferon inducible gene expression in response to viral infection. Binds ssRNA, dsRNA and dsDNA and can promote the binding of DDX58/RIG-...
TMPH-00979 DDX3Y Protein, Human, Recombinant (His & Myc) Human Baculovirus Insect Cells
DDX3Y Protein, Human, Recombinant (His & Myc) is expressed in Baculovirus.
TMPH-00976 DDX19A Protein, Human, Recombinant (His & SUMO) Human E. coli
DDX19A Protein, Human, Recombinant (His & SUMO) is expressed in E. coli.
TMPH-00977 DDX3X Protein, Human, Recombinant (B2M & His) Human E. coli
DDX3X Protein, Human, Recombinant (B2M & His) is expressed in E. coli.
TMPH-00978 DDX3X Protein, Human, Recombinant (His & Myc) Human Baculovirus Insect Cells
DDX3X Protein, Human, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag. The predicted molecular weight is 77 kDa and the accession number is O00571.
TMPH-00973 DHX36 Protein, Human, Recombinant (His & Myc) Human E. coli
DHX36 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 18.2 kDa and the accession number is Q9H2U1.
TMPH-00975 DDX1 Protein, Human, Recombinant (His & Myc) Human E. coli
DDX1 Protein, Human, Recombinant (His & Myc) is expressed in E. coli.
TMPH-01901 DDX53 Protein, Human, Recombinant (His & Myc) Human E. coli
N/A. DDX53 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 76.2 kDa and the accession number is Q86TM3.
TMPY-00323 Hepatitis C virus (HCV-1a) NS3 protease/helicase immunodominant region Protein (aa 1356-1459, GST) HCV E. coli
HCV NS3 displays three enzymatic activities: serine protease, NTPase, and RNA helicase. HCV NS3 serine protease, in association with NS4A, is responsible for the cleavages of NS3-NS4A, NS4A-NS4B, NS4B-NS5A, and NS5A-NS5B...
TMPH-01306 EIF4A1 Protein, Human, Recombinant (His & Myc) Human E. coli
ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary str...
TMPJ-01450 SARS-CoV-2 Helicase Protein (His & MBP) SARS-CoV-2 E. coli
The non—structural protein 13 (nsp13) of SARS—CoV 2 is a helicase that separates double—stranded RNA or DNA with a 5'—3' polarity, using the energy of nucleotide hydrolysis. A basic biochemical characterization of nsp13 ...
TMPY-05752 SARS-CoV-2 3CLpro/3C-like protease Protein (His) SARS-CoV-2 Baculovirus Insect Cells
3C-like protease (3CLpro) is the main protease of Humann Coronavirus. 3C-like protease (3CLpro) is a key enzyme, as it cleaves several sites to produce non-structural proteins that are essential for genome replication an...
TMPY-05727 SARS-CoV-2 3CLpro/3C-like protease Protein (His & Avi) SARS-CoV-2 E. coli
3C-like protease (3CLpro) is the main protease of Humann Coronavirus. 3C-like protease (3CLpro) is a key enzyme, as it cleaves several sites to produce non-structural proteins that are essential for genome replication an...
TMPY-02060 Human Enterovirus 71 VP0 Protein (His & GST) EV71 Baculovirus Insect Cells
Human enterovirus 71 genome polyprotein is a member of the picornaviruses polyprotein family. It contains two peptidase C3 domains, one RdRp catalytic domain, one SF3 helicase domain. Genome polyprotein is cleaved into t...
TMPH-02314 XRCC5 Protein, Human, Recombinant (His & MBP) Human Baculovirus Insect Cells
Single-stranded DNA-dependent ATP-dependent helicase that plays a key role in DNA non-homologous end joining (NHEJ) by recruiting DNA-PK to DNA. Required for double-strand break repair and V(D)J recombination. Also has a...
TMPH-02315 XRCC5 Protein, Human, Recombinant (His & Myc) Human E. coli
Single-stranded DNA-dependent ATP-dependent helicase that plays a key role in DNA non-homologous end joining (NHEJ) by recruiting DNA-PK to DNA. Required for double-strand break repair and V(D)J recombination. Also has a...
DHX9 Protein, Human, Recombinant (His & SUMO)
TMPH-00974
Species: Human
Expression System: E. coli
DDX5 Protein, Human, Recombinant (His & Myc)
TMPH-01900
Species: Human
Expression System: E. coli
DHX33 Protein, Human, Recombinant (His)
TMPH-00980
Species: Human
Expression System: E. coli
DDX39B Protein, Human, Recombinant (GST)
TMPH-02133
Species: Human
Expression System: E. coli
DDX60 Protein, Human, Recombinant (His)
TMPH-01902
Species: Human
Expression System: E. coli
DDX3Y Protein, Human, Recombinant (His & Myc)
TMPH-00979
Species: Human
Expression System: Baculovirus Insect Cells
DDX19A Protein, Human, Recombinant (His & SUMO)
TMPH-00976
Species: Human
Expression System: E. coli
DDX3X Protein, Human, Recombinant (B2M & His)
TMPH-00977
Species: Human
Expression System: E. coli
DDX3X Protein, Human, Recombinant (His & Myc)
TMPH-00978
Species: Human
Expression System: Baculovirus Insect Cells
DHX36 Protein, Human, Recombinant (His & Myc)
TMPH-00973
Species: Human
Expression System: E. coli
DDX1 Protein, Human, Recombinant (His & Myc)
TMPH-00975
Species: Human
Expression System: E. coli
DDX53 Protein, Human, Recombinant (His & Myc)
TMPH-01901
Species: Human
Expression System: E. coli
Hepatitis C virus (HCV-1a) NS3 protease/helicase immunodominant region Protein (aa 1356-1459, GST)
TMPY-00323
Species: HCV
Expression System: E. coli
EIF4A1 Protein, Human, Recombinant (His & Myc)
TMPH-01306
Species: Human
Expression System: E. coli
SARS-CoV-2 Helicase Protein (His & MBP)
TMPJ-01450
Species: SARS-CoV-2
Expression System: E. coli
SARS-CoV-2 3CLpro/3C-like protease Protein (His)
TMPY-05752
Species: SARS-CoV-2
Expression System: Baculovirus Insect Cells
SARS-CoV-2 3CLpro/3C-like protease Protein (His & Avi)
TMPY-05727
Species: SARS-CoV-2
Expression System: E. coli
Human Enterovirus 71 VP0 Protein (His & GST)
TMPY-02060
Species: EV71
Expression System: Baculovirus Insect Cells
XRCC5 Protein, Human, Recombinant (His & MBP)
TMPH-02314
Species: Human
Expression System: Baculovirus Insect Cells
XRCC5 Protein, Human, Recombinant (His & Myc)
TMPH-02315
Species: Human
Expression System: E. coli
カタログ番号 製品名
L1710 Anti-COVID-19 Compound Library

1133 compounds
A unique collection of 1133 compounds with confirmed anti-SARS-CoV-2 activity or potential activity and part of them are broad-spectrum antiviral agents;